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Product Name
Anti-c-Jun Rabbit antibody
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Description
c-Jun Rabbit polyclonal antibody
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Tested applications
WB, ICC/IF, IP
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Species reactivity
Human
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Alternative names
Activator Protein 1;AP 1;AP1;cJun;Enhancer Binding Protein AP1;Jun Activation Domain Binding Protein;JUN;Jun oncogene;JUN protein;Jun proto oncogene;JUN_HUMAN;JUNC;Oncogene JUN;p39;Proto oncogene c jun;Proto oncogene cJun;Proto-oncogene c-jun;Transcriptio antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide of human c-Jun
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Clonality
Polyclonal
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Formulation
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage instructions
Store at -20°C. Stable for 12 months from date of receipt.
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Applications
WB: 1/1000
ICC/IF: 1/50
IP: 1/20
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Validations
Western blot detection of c-Jun in 3T3 cell lysates using c-Jun Rabbit pAb(1:1000 diluted).Predicted band size:36KDa.Observed band size:48,43KDa.
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Background
Swiss-Prot Acc.P05412.Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells (PubMed:24623306). Binds to the USP28 promoter in colorectal cancer (CRC) cells (PubMed:24623306).
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"