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Product Name
Anti-BTF3 Rabbit antibody
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Description
BTF3 Rabbit polyclonal antibody
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Tested applications
WB, IHC-P, ICC/IF, FC, IP
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Species reactivity
Human, Mouse, Rat
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Alternative names
NACB; BTF3a; BTF3b; BETA-NAC antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: Recombinant protein of human BTF3
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Clonality
Polyclonal
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Formulation
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage instructions
Store at -20°C. Stable for 12 months from date of receipt.
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Applications
WB: 1/1000
IHC: 1/50
ICC/IF: 1/50
FC: 1/50
IP: 1/20
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Validations
Western blot detection of BTF3 in C6,3T3 cell lysates using BTF3 Rabbit pAb(1:1000 diluted).Predicted band size:22kDa.Observed band size:22kDa.
Immunohistochemistry of BTF3 in paraffin-embedded Human breast cancer tissue using BTF3 Rabbit pAb at dilution 1/50
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Background
Swiss-Prot Acc.P20290.When associated with NACA, prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. BTF3 is also a general transcription factor that can form a stable complex with RNA polymerase II. Required for the initiation of transcription.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"