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Product Name
Anti-Bim Rabbit antibody
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Description
Bim Rabbit polyclonal antibody
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Tested applications
WB, IHC-P, ICC/IF, IP, FC
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Species reactivity
Human, Mouse, Rat
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthesized peptide derived from human Bim
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Clonality
Polyclonal
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Formulation
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage instructions
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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Applications
WB: 1/500-1/1000
IHC: 1/50-1/100
ICC/IF: 1/50-1/100
IP: 1/40
FC: 1/50
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Validations
Immunofluorescent analysis of Raji cells, using Bim Antibody.
Immunohistochemical analysis of paraffin-embedded human cervix cancer, using Bim Antibody.
Western blot analysis of Bim expression in A431 cell lysate.
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Background
Swiss-Prot Acc.O43521.Bim a pro-apoptotic member of the BCL-2 protein family. Interacts with other members of the BCL-2 protein family, including BCL2, BCL2L1/BCL-X(L), and MCL1, and act as an apoptotic activator. Its expression can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role in neuronal and lymphocyte apoptosis.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"