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Product Name
Anti-bFGF/FGF2 antibody
- Documents
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Description
Rabbit polyclonal to bFGF/FGF2
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Tested applications
ELISA, WB, IP
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Species reactivity
Human bFGF / FGF2
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Alternative names
BFGF antibody; FGFB antibody; FGF-2 antibody; HBGF-2 antibody; Fgfb antibody; bFGF antibody; Fgf-2 antibody; bFGF antibody; BFGF antibody; DN-452A22.6 antibody; Fgf2 antibody; FGF2 antibody; Fgf-2 antibody; Fgfb antibody; FGFB antibody; HBGF-2 antibody
- Immunogen
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Isotype
Rabbit IgG
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Preparation
Produced in rabbits immunized with purified, recombinant Human bFGF / FGF2 (rhFGF2; NP_001997.5; Pro 143-Ser 288). bFGF specific IgG was purified by human bFGF affinity chromatography.
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Clonality
Polyclonal
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Formulation
0.2 μm filtered solution in PBS with 5% trehalose
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Storage instructions
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles. -
Applications
WB: 10-30 μg/mL
ELISA: 0.5-1.0 μg/mL
This antibody can be used at 0.5-1.0 μg/mL with the appropriate secondary reagents to detect Human bFGF. The detection limit for Human bFGF is 0.00245 ng/well.
IP: 4-6 μg/mg of lysate
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Validations
bFGF / FGF2 Antibody, Rabbit PAb, Antigen Affinity Purified, Western blot
bFGF / FGF2 Antibody, Rabbit PAb, Antigen Affinity Purified
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Background
Basic fibroblast growth factor (bFGF), also known as FGF2, is a member of the fibroblast growth factor (FGF) family. It is a highly specific chemotactic and mitogenic factor for many cell types, appears to be involved in remodeling damaged tissue, such as ulcer healing, vascular repair, traumatic brain injury (TBI). bFGF is a critical component of human embryonic stem cell culture medium. In addition, bFGF protein is a heparin-binding cationic protein involved in a variety of pathological conditions including angiogenesis and solid tumour growth. Thus, bFGF is regarded as a target for cancers chemopreventive and therapeutic strategies. bFGF/FGF2 Protein & Antibody Products
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References
- Takayama S,et al. (2001) Periodontal regeneration by FGF-2 (bFGF) in primate models. J Dent Res. 80(12): 2075-9.
- Niu YJ, et al. (2004) Therapeutic effect of bFGF on retina ischemia-reperfusion injury. Chin Med J (Engl). 117(2): 252-7.
- Zhang Y,et al. (2004) Expression of aFGF, bFGF, and FGFR1 in ovarian epithelial neoplasm. Chin Med J (Engl). 117(4): 601-3.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"