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Product Name
Human bFGF/FGF2 recombinant protein
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Description
Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro.
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Protein name
Fibroblast growth factor 2
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Protein short names
HBGF-2; BFGF; DN-452A22.6; FGFB; FGF-2; FGF2
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Uniprot ID
P09038
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Gene Name
FGF2; FGFB
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the mature form of human bFGF (NP_001997.5) (Pro 143-Ser 288) was expressed, with an additional Met at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human bFGF is a disulfide-linked homodimeric protein. The reduced monomer consists of 147 amino acids and has a calculated molecular mass of 16.5 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of bFGF is approximately 17 kDa.
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Purity
> 95 % as determined by SDS-PAGE
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Activity
Measured in a cell proliferation assay using BALB/c 3T3 mouse embryonic fibroblasts.
The ED50 for this effect is typically 0.02-0.1 ng/ml. -
Validations
Human bFGF / FGF2 Protein SDS-PAGE
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