Alpha-2-macroglobulin antibody

Alpha-2-macroglobulin antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

Alpha-2-macroglobulin Mouse Monoclonal antibody. Positive WB detected in HepG2 cells, human brain tissue. Positive IP detected in human plasma tissue. Positive IHC detected in human liver tissue. Observed molecular weight by Western-blot: 185 kDa

ELISA, IHC, WB, IP

Human; other species not tested.

A2M antibody; Alpha 2 M antibody; alpha 2 macroglobulin antibody; CPAMD5 antibody; DKFZp779B086 antibody; FWP007 antibody; S863 7 antibody; α-2M antibody

Mouse IgG2a

This antibody was obtained by immunization of Alpha-2-macroglobulin recombinant protein (Accession Number: NM_001347423). Purification method: Protein A purified.

Monoclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

alpha-2-macroglobulin, also known as α2-macroglobulin (α2M and A2M), is a protein abundant in the plasma of vertebrates and several invertebrates. A2M is an evolutionarily conserved arm of the innate immune system. It also mediates the proliferation of T cells and macrophages. A2M acts as a nonspecific protease inhibitor involved in the host defense mechanism that inactivates both endogenous and exogenous proteases, including trypsin, thrombin and collagenase. Even though A2M is produced predominantly by the liver, it may also be expressed in the reproductive tract, heart, and brain, and may have important roles in many physiological processes and medical illnesses including Alzheimer’s disease.