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Product Name
Human AKR1C2 / DDH2 (His Tag) recombinant protein
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Description
Works in concert with the 5-alpha/5-beta-steroid reductases to convert steroid hormones into the 3-alpha/5-alpha and 3-alpha/5-beta-tetrahydrosteroids. Catalyzes the inactivation of the most potent androgen 5-alpha-dihydrotestosterone (5-alpha-DHT) to 5-alpha-androstane-3-alpha,17-beta-diol (3-alpha-diol). Has a high bile-binding ability.
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Protein name
Aldo-keto reductase family 1 member C2
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Protein short names
HBAB; TRANS-1; DD/BABP; DD; DDH2; DIHYDRODIOL DEHYDROGENASE 2; MCDR2; PSEUDO-CHLORDECONE REDUCTASE; AKR1C-PSEUDO; TYPE III; AKR1C2; CHLORDECONE REDUCTASE HOMOLOG HAKRD; DD2; BABP; 2-DIHYDROBENZENE-1; DD-2; HAKRD; BILE ACID BINDING PROTEIN; 3-ALPHA HYDROXYSTEROID DEHYDROGENASE; MEMBER C2; SRXY8; TYPE II DIHYDRODIOL DEHYDROGENASE; 2-DIOL DEHYDROGENASE; ALDO-KETO REDUCTASE FAMILY 1 MEMBER C2; ALDO-KETO REDUCTASE FAMILY 1; 3-ALPHA-HSD3
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Uniprot ID
P52895
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Gene Name
AKR1C2; DDH2
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the mature form of human AKR1C2 (P52895-1) (Met1-Tyr323) was expressed with a polyhistidine tag at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human AKR1C2 consists of 338 amino acids and predicts a molecular mass of 38.6 KDa. It migrates as an approximately 37 KDa band in SDS-PAGE under reducing conditions.
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Purity
> 90 % as determined by SDS-PAGE
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Validations
Human AKR1C2 Protein (His Tag) SDS-PAGE
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