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Product Name
Ajuba antibody
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Description
Ajuba Rabbit Polyclonal antibody. Positive WB detected in Transfected HEK-293 cells. Positive IHC detected in human stomach tissue, human prostate cancer tissue.
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
Ajuba antibody; JUB antibody; Protein ajuba antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Ajuba recombinant protein (Accession Number: NM_032876). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IHC: 1:20-1:200
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Validations
Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:107921(JUB Antibody) at dilution of 1:800
Immunohistochemistry of paraffin-embedded human stomach tissue slide using Catalog No:107921(JUB Antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemistry of paraffin-embedded human stomach tissue slide using Catalog No:107921(JUB Antibody) at dilution of 1:50 (under 40x lens)
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Background
Ajuba belongs to the LIM domain proteins, which are involved in the assembly of the extracellular matrix and, along with associated proteins, regulate target genes that connect the extracellular matrix and the cytoskeleton. Ajuba consists of three LIM domains at the C-terminal and is located in the cytoplasm where it interacts with a variety of other proteins. Ajuba contributes to the formation or strengthening of cell–cell adhesion and regulates cell growth and differentiation decisions. Ajuba participates in the assembly of the extracellular matrix. Ajuba also plays an important role in some diseases.
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References
- Zhang L, Zhou Y, Cheng C. Genomic analyses reveal mutational signatures and frequently altered genes in esophageal squamous cell carcinoma. American journal of human genetics. 96(4):597-611. 2015.
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