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Product Name
Mouse AGRP (Fc Tag) recombinant protein
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Description
Plays a role in weight homeostasis. Involved in the control of feeding behavior through the central melanocortin system. Acts as alpha melanocyte-stimulating hormone antagonist by inhibiting cAMP production mediated by stimulation of melanocortin receptors within the hypothalamus and adrenal gland. Has very low activity with MC5R. Is an inverse agonist for MC3R and MC4R being able to suppress their constitutive activity (By similarity). It promotes MC3R and MC4R endocytosis in an arrestin-dependent manner (By similarity).
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Protein name
Agouti-related protein
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Protein short names
MGC118963; ASIP2; AGRP; ART; AGRT
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Uniprot ID
Q3UU47
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Gene Name
Agrp; Agrt; Art
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the mouse Agrp (NP_031453.1) (Ser82-Thr131) was expressed with the Fc region of human IgG1 at the N-terminus.
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Protein Species
Mouse
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Molecular weight
The recombinant mouse Agrp consists 310 amino acids and predicts a molecular mass of 34.1 kDa.
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Purity
> 80 % as determined by SDS-PAGE.
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Validations
Mouse AGRP Protein (Fc Tag) SDS-PAGE
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