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Product Name
ADRP antibody
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Description
ADRP Mouse Monoclonal antibody. Positive WB detected in human adipose tissue. Observed molecular weight by Western-blot: 47-52 kDa
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Tested applications
ELISA, WB
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Species reactivity
Human; other species not tested.
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Alternative names
ADFP antibody; Adipophilin antibody; ADRP antibody; Perilipin 2 antibody; PLIN2 antibody
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Isotype
Mouse IgG1
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Preparation
This antibody was obtained by immunization of ADRP recombinant protein (Accession Number: NM_001122). Purification method: Protein G purified.
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Clonality
Monoclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
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Validations
human adipose tissue were subjected to SDS PAGE followed by western blot with Catalog No:107560(ADRP Antibody) at dilution of 1:1000
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Background
ADRP (adipocyte differentiation related protein) also known as ADFP, adipophilin, or perilipin-2, is a member of PAT family which is responsible for the transportation of lipids and the formation of lipid droplets. ADRP is localized on the surface of lipid droplets in a variety of tissues and cell lines. ADRP is not detected in undifferentiated cells but increases rapidly to high levels when adipocyte precursors differentiate into adipocytes. Anti-ADRP antibody is a reliable and sensitive marker for lipid droplet. Enhanced expression of ADRP is linked to diseases with abnormal lipid storage, including hepatic steatosis, atherosclerosis and diabetes. Immunohistochemistry of ADRP may facilitate histomorphological diagnosis of these diseases.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"