Human CD38 (His Tag) recombinant protein
Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system.
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1
Protein short names
ADPRC1; T10; CD38-RS1; CD38
A DNA sequence encoding the extracellular domain of human CD38 (NP_001766.2) (Val 43-Ile 300) with a C-terminal polyhistidine tag was expressed.
The secreted recombinant human CD38 comprises 269 amino acids with a predicted molecular mass of 31.3 kDa. As a result of glycosylation, rhCD38 migrates as an approximately 43-45 kDa band in SDS-PAGE under reducing conditions.
> 97 % as determined by SDS-PAGE
Human CD38 Protein (His Tag) SDS-PAGE
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