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Cynomolgus 14-3-3 beta/YWHAB recombinant protein

Cat.#: 502997

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Product Information

  • Product Name
    Cynomolgus 14-3-3 beta/YWHAB recombinant protein
  • Documents
  • Description
    Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by SRPK2 (By similarity).
  • Protein name
    14-3-3 protein beta/alpha
  • Protein short names
    GW128; 14-3-3 PROTEIN BETA; 1300003C17RIK; HEL-S-1; HS1; YWHAB; RP23-321M14.1; KCIP-1; YWHAA
  • Uniprot ID
    Q4R572
  • Gene Name
    YWHAB; QccE-16215
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the mature form of Cynomolgus (Macaca fascicularis) YWHAB (Q4R572-2) (Met 2-Asn 244) was expressed and purified, with an initial Met.
  • Protein Species
    Cynomolgus
  • Molecular weight
    The recombinant Cynomolgus YWHAB consists of 246 amino acids and has a calculated molecular mass of 27.8 kDa. It migrates as an approximately 30 kDa band in SDS-PAGE under reducing conditions.
  • Purity
    > 90 % as determined by SDS-PAGE
  • Validations

    Cynomolgus 14-3-3 beta / YWHAB Protein SDS-PAGE

    Cynomolgus 14-3-3 beta / YWHAB Protein SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"