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Human 14-3-3 beta/YWHAB (GST Tag) recombinant protein

Cat.#: 502555

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Product Information

  • Product Name
    Human 14-3-3 beta/YWHAB (GST Tag) recombinant protein
  • Documents
  • Description
    Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by SRPK2.
  • Protein name
    14-3-3 protein beta/alpha
  • Protein short names
    HEL-S-1; 1300003C17RIK; GW128; 14-3-3 PROTEIN BETA; KCIP-1; YWHAA; RP23-321M14.1; HS1; YWHAB
  • Uniprot ID
    V9HWD6
  • Gene Name
    YWHAB
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human YWHAB (NP_003395.1) (Met 1-Asn 246) was fused with the GST tag at the N-terminus.
  • Protein Species
    Human
  • Molecular weight
    The recombinant human YWHAB/GST chimera consists of 478 amino acids and has a predicted molecular mass of 54.9 kDa. It migrates as an approxiamtely 52 kDa band in SDS-PAGE under reducing conditions.
  • Purity
    > 96 % as determined by SDS-PAGE
  • Validations

    Human 14-3-3 beta / YWHAB Protein (GST Tag) SDS-PAGE

    Human 14-3-3 beta / YWHAB Protein (GST Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"