Anti-YWHAB antibody

Anti-YWHAB antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

Rabbit Polyclonal to Cynomolgus YWHAB

IP

Cynomolgus 14-3-3 beta / YWHAB

HS1 antibody; GW128 antibody; YWHAA antibody; KCIP-1 antibody; HEL-S-1 antibody; 1300003C17Rik antibody; HS1 antibody; 1300003C17Rik antibody; 14-3-3 protein beta antibody; 14-3-3 protein beta antibody; GW128 antibody; KCIP-1 antibody; RP23-321M14.1 antibody; YWHAB antibody; Ywhab antibody

Rabbit IgG

Produced in rabbits immunized with purified, recombinant Cynomolgus 14-3-3 beta / YWHAB . 14-3-3 beta / YWHAB specific IgG was purified by Cynomolgus 14-3-3 beta / YWHAB affinity chromatography.

Polyclonal

0.2 μm filtered solution in PBS

This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

14-3-3 beta / YWHAB is a member of the 14-3-3 proteins family. 14-3-3 proteins are a group of highly conserved proteins that are involved in many vital cellular processes such as metabolism, protein trafficking, signal transduction, apoptosis and cell cycle regulation. 14-3-3 proteins are mainly localized in the synapses and neuronal cytoplasm, and seven isoforms have been identified in mammals. This family of proteins was initially identified as adaptor proteins which bind to phosphoserine-containing motifs. Binding motifs and potential functions of 14-3-3 proteins are now recognized to have a wide range of functional relevance. 14-3-3 beta / YWHAB is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. 14-3-3 beta / YWHAB interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. 14-3-3 beta / YWHAB has also been implicated in the pathogenesis of small cell lung cancer. 14-3-3 beta / YWHAB binding negatively regulates RSK1 activity to maintain signal specificity and that association/dissociation of the 14-3-3beta-RSK1 complex is likely to be important for mitogen-mediated RSK1 activation.