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Zolbetuximab (Synonyms: CLAUDIXIMAB)

Cat.#: 176823

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Product Information

  • Product Name
    Zolbetuximab (Synonyms: CLAUDIXIMAB)
  • Documents
  • Description
    Anti-CLDN18.2 Antibody (Zolbetuximab)
  • Tested applications
    ELISA
  • Species reactivity
    Human CLDN18.2
  • Alternative names
    CLAUDIXIMAB antibody
  • Isotype
    IgG1
  • Preparation
    Recombinant expression and purified from CHO cells.
  • Clonality
    Monoclonal
  • Formulation
    0.1 M Pro-Ac, 20 mM Arg, pH 5.0
  • Storage instructions
    -80°C for 2 years under sterile conditions; -20°C for 1 year under sterile conditions; Avoid repeated freeze-thaw cycles.
  • Validations

    SDS-PAGE

    SDS-PAGE

    Anti-CLDN18.2 Antibody (zolbetuximab) on SDS-PAGE under reducing (R) condition. The purity of the protein is greater than 95%.

    SEC-HPLC

    SEC-HPLC

    The purity of Anti-CLDN18.2 Antibody (zolbetuximab) is 96.05%, determined by SEC-HPLC.

    Bioactivity: ELISA

    Bioactivity: ELISA

    Immobilized human CLDN18.2 VLP at 2 ug/mL can bind Anti-CLDN18.2 Antibody (zolbetuximab), EC50=0.07951 ug/mL.

    Research in vivo

    Research in vivo

    Zolbetuximab inhibited the tumor growth of CLDN18.2-MC38 (Mouse colorectal cancer cells) on C57BL/6N mice. The result showed significant anti-tumor effects, with an tumor inhibition rate (TGI) of 42.3% at 10 mpk at D25.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"