ZnT3 antibody

Cat.#: 117256

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Product Information

  • Product Name
    ZnT3 antibody
  • Documents
  • Description
    ZnT3 Rabbit Polyclonal antibody. Positive WB detected in mouse brain tissue. Positive IHC detected in human brain tissue. Observed molecular weight by Western-blot: 42kd,48kd
  • Tested applications
    ELISA, WB, IHC
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    SLC30A3 antibody; Zinc transporter 3 antibody; ZnT 3 antibody; ZNT3 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of ZnT3 recombinant protein (Accession Number: NM_003459). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:500-1:5000

    IHC: 1:20-1:200

  • Validations

    mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:117256(SLC30A3 antibody) at dilution of 1:1000

    mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:117256(SLC30A3 antibody) at dilution of 1:1000

    Immunohistochemical of paraffin-embedded human brain using Catalog No:117256(SLC30A3 antibody) at dilution of 1:100 (under 10x lens)

    Immunohistochemical of paraffin-embedded human brain using Catalog No:117256(SLC30A3 antibody) at dilution of 1:100 (under 10x lens)

    Immunohistochemical of paraffin-embedded human brain using Catalog No:117256(SLC30A3 antibody) at dilution of 1:100 (under 40x lens)

    Immunohistochemical of paraffin-embedded human brain using Catalog No:117256(SLC30A3 antibody) at dilution of 1:100 (under 40x lens)

  • Background
    SLC30A3 represents solute carrier family 30 (zinc transporter), member 3
  • References
    • Kanninen KM, Grubman A, Caragounis A. Altered biometal homeostasis is associated with CLN6 mRNA loss in mouse neuronal ceroid lipofuscinosis. Biology open. 2(6):635-46. 2013.
    • Grubman A, Lidgerwood GE, Duncan C. Deregulation of subcellular biometal homeostasis through loss of the metal transporter, Zip7, in a childhood neurodegenerative disorder. Acta neuropathologica communications. 2:25. 2014.
    • Kaneko M, Noguchi T, Ikegami S. Zinc transporters ZnT3 and ZnT6 are downregulated in the spinal cords of patients with sporadic amyotrophic lateral sclerosis. Journal of neuroscience research. 93(2):370-9. 2015.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"