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Product Name
ZnT3 antibody
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Description
ZnT3 Rabbit Polyclonal antibody. Positive WB detected in mouse brain tissue. Positive IHC detected in human brain tissue. Observed molecular weight by Western-blot: 42kd,48kd
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
SLC30A3 antibody; Zinc transporter 3 antibody; ZnT 3 antibody; ZNT3 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of ZnT3 recombinant protein (Accession Number: NM_003459). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:20-1:200
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Validations
mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:117256(SLC30A3 antibody) at dilution of 1:1000
Immunohistochemical of paraffin-embedded human brain using Catalog No:117256(SLC30A3 antibody) at dilution of 1:100 (under 10x lens)
Immunohistochemical of paraffin-embedded human brain using Catalog No:117256(SLC30A3 antibody) at dilution of 1:100 (under 40x lens)
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Background
SLC30A3 represents solute carrier family 30 (zinc transporter), member 3
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References
- Kanninen KM, Grubman A, Caragounis A. Altered biometal homeostasis is associated with CLN6 mRNA loss in mouse neuronal ceroid lipofuscinosis. Biology open. 2(6):635-46. 2013.
- Grubman A, Lidgerwood GE, Duncan C. Deregulation of subcellular biometal homeostasis through loss of the metal transporter, Zip7, in a childhood neurodegenerative disorder. Acta neuropathologica communications. 2:25. 2014.
- Kaneko M, Noguchi T, Ikegami S. Zinc transporters ZnT3 and ZnT6 are downregulated in the spinal cords of patients with sporadic amyotrophic lateral sclerosis. Journal of neuroscience research. 93(2):370-9. 2015.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"