-
Product Name
ZMPSTE24 antibody
- Documents
-
Description
ZMPSTE24 Rabbit Polyclonal antibody. Positive IP detected in PC-3 cells. Positive WB detected in PC-3 cells. Positive IF detected in PC-3 cells. Observed molecular weight by Western-blot: 55 kDa
-
Tested applications
ELISA, WB, IF, IP
-
Species reactivity
Human,Mouse,Rat; other species not tested.
-
Alternative names
CAAX prenyl protease 1 homolog antibody; FACE 1 antibody; FACE1 antibody; FLJ14968 antibody; STE24 antibody; Ste24p antibody; ZMPSTE24 antibody
-
Isotype
Rabbit IgG
-
Preparation
This antibody was obtained by immunization of ZMPSTE24 recombinant protein (Accession Number: NM_005857). Purification method: Antigen affinity purified.
-
Clonality
Polyclonal
-
Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
-
Storage instructions
Store at -20℃. DO NOT ALIQUOT
-
Applications
Recommended Dilution:
WB: 1:200-1:2000
IP: 1:200-1:1000
IF: 1:10-1:100
-
Validations
PC-3 cells were subjected to SDS PAGE followed by western blot with Catalog No:116940(ZMPSTE24 antibody) at dilution of 1:400
IP Result of anti-ZMPSTE24 (IP:Catalog No:116940, 4ug; Detection:Catalog No:116940 1:300) with PC-3 cells lysate 3200ug.
Immunofluorescent analysis of PC-3 cells using Catalog No:116940(ZMPSTE24 Antibody) at dilution of 1:25 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
-
Background
ZMPSTE24(CAAX prenyl protease 1 homolog) gene encodes a zinc metalloproteinase involved in the processing of farnesylated proteins(PubMed: 10373325). The significance of ZMPSTE24 in human disease stems from its role as an enzyme necessary for the correct processing and maturation of lamin A ,an intermediate filament component of the nuclear envelope (PubMed: 16297189).
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"