YY1 antibody

YY1 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

YY1 Rabbit Polyclonal antibody. Positive WB detected in Jurkat cells, A549 cells, HEK-293 cells, HeLa cells. Positive IP detected in HeLa cells. Observed molecular weight by Western-blot: 68-70 kDa

ELISA, WB, IP

Human; other species not tested.

DELTA antibody; Delta transcription factor antibody; INO80 complex subunit S antibody; INO80S antibody; NF E1 antibody; UCRBP antibody; Yin and yang 1 antibody; YIN YANG 1 antibody; YY 1 antibody; YY1 antibody; YY1 transcription factor antibody

Rabbit IgG

This antibody was obtained by immunization of YY1 recombinant protein (Accession Number: NM_003403). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

YY1, also named as DELTA, INO80S and NF-E1, contains four C2H2-type zinc fingers and belongs to the YY transcription factor family. YY1 is a multifunctional transcription factor that exhibits positive and negative control on a large number of cellular and viral genes by binding to sites overlapping the transcription start site. YY1 may direct histone deacetylases and histone acetyltransferases to a promoter in order to activate or repress the promoter, thus implicating histone modification in the YY1. The open reading frame of the human YY1 cDNA encodes a protein of 414 amino acids with a predicted molecular weight of 44 kDa. However, YY1 migrates on SDS gels as a 65–68 kDa protein, probably due to the structure of the protein. It is a ubiquitously expressed transcription factor with fundamental roles in embryogenesis, differentiation, replication and proliferation. This is a rabbit polyclonal antibody raised against full length YY1 of human origin.

• Liu XC, Lian W, Zhang LJ. Interleukin-18 Down-Regulates Multidrug Resistance-Associated Protein 2 Expression through Farnesoid X Receptor Associated with Nuclear Factor Kappa B and Yin Yang 1 in Human Hepatoma HepG2 Cells. PloS one. 10(8):e0136215. 2015.