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XPR1 antibody

Cat.#: 116996

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Product Information

  • Product Name
    XPR1 antibody
  • Documents
  • Description
    XPR1 Rabbit Polyclonal antibody. Positive FC detected in Jurkat cells. Positive IHC detected in human heart tissue. Positive WB detected in Jurkat cells. Observed molecular weight by Western-blot: 82-84kd
  • Tested applications
    ELISA, WB, IHC, FC
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    FLJ90308 antibody; Protein SYG1 homolog antibody; SYG1 antibody; X receptor antibody; XPR1 antibody
  • Immunogen
    Human XPR1 Recombinant protein (GST tag)
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of XPR1 recombinant protein (Accession Number: NM_001135669). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:500-1:5000

    IHC: 1:20-1:200

  • Validations

    Jurkat cells were subjected to SDS PAGE followed by western blot with Catalog No:116996(XPR1 antibody) at dilution of 1:500

    Jurkat cells were subjected to SDS PAGE followed by western blot with Catalog No:116996(XPR1 antibody) at dilution of 1:500

    Immunohistochemical of paraffin-embedded human heart using Catalog No:116996(XPR1 antibody) at dilution of 1:100 (under 10x lens)

    Immunohistochemical of paraffin-embedded human heart using Catalog No:116996(XPR1 antibody) at dilution of 1:100 (under 10x lens)

    Immunohistochemical of paraffin-embedded human heart using Catalog No:116996(XPR1 antibody) at dilution of 1:100 (under 40x lens)

    Immunohistochemical of paraffin-embedded human heart using Catalog No:116996(XPR1 antibody) at dilution of 1:100 (under 40x lens)

    1X10^6 Jurkat cells were stained with 0.2ug XPR1 antibody (Catalog No:116996, red) and control antibody (blue). Fixed with 90% MeOH blocked with 3% BSA (30 min). Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L) with dilution 1:1000.

    1X10^6 Jurkat cells were stained with 0.2ug XPR1 antibody (Catalog No:116996, red) and control antibody (blue). Fixed with 90% MeOH blocked with 3% BSA (30 min). Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L) with dilution 1:1000.

  • Background
    XPR1 is a receptor for xenotropic and polytropic murine leukemia retroviruses and homolog of yeast Syg1 and plant Pi transporter PHO1 (PMID: 20633538). XPR1 has been identifies as an atypical G-protein-coupled receptor. Xenotropic or polytropic retrovirus binding to XPR1 can disrupt the cAMP-mediated signaling function of Xpr1, leading to the apoptosis of infected cells (PMID: 22090134).

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"