XDH antibody

XDH antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

XDH Rabbit Polyclonal antibody. Positive IHC detected in human heart tissue. Positive WB detected in mouse liver tissue. Observed molecular weight by Western-blot: 147-150kd

ELISA, WB, IHC

Human,Mouse,Rat; other species not tested.

xanthine dehydrogenase antibody; Xanthine Oxidase antibody; Xanthine oxidoreductase antibody; XDH antibody; XDHA antibody; XOR antibody

Rabbit IgG

This antibody was obtained by immunization of Peptide (Accession Number: NM_000379). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

XDH, also named as XDHA, XO and XD, belongs to the xanthine dehydrogenase family. It catalyzes the last two steps of purine catabolism in man, formation of the end product uric acid from hypoxanthine and xanthine. The mammalian enzyme is synthesized as a dehydrogenase (XDH), which uses NAD as the electron acceptor, but it can be converted into an oxidase (XO) both in vivo and in vitro.This gene encodes a protein of 150 kDa and the 150 kDa polypeptide can be processed into a fragment of 130 kDa and further to 85 kDa by spontaneous proteolytic cleavage(PMID:9989587). In addition, the full length polypeptide can be also partially processed into a 87 kDa and 59 kDa fragments(PMID:21528298). It also can exsit as a homodimer(PMID:9989587). This antibody is specific to XDH.