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Product Name
Human XPNPEP2 (His Tag) recombinant protein
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Description
A metalloprotease that may play a role in the inflammatory process and other reactions produced in response to injury or infection. May also play a role in the metabolism of the vasodilator bradykinin.
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Protein name
Xaa-Pro aminopeptidase 2
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Protein short names
APP2; XPNPEP2; RP23-351G20.1; RP4-753P9.2; MAPP; AEACEI; 9030008G12RIK
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Uniprot ID
O43895
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Gene Name
XPNPEP2
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human XPNPEP2 (O43895) (Met 1-Ala 650) without the pro peptide was expressed, with a polyhistidine tag at the C-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human XPNPEP2 consists of 640 amino acids and predictes a molecular mass of 72 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh XPNPEP2 is approximately 80 kDa due to glycosylation.
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Purity
> 97 % as determined by SDS-PAGE
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Activity
Measured by its ability to cleave the fluorogenic peptide substrate, H-Lys(2-Aminobenzoyl)Pro-Pro-pNitroanilide(K(Abz)PP-pNA).
The specific activity is > 300 pmoles/min/μg. -
Validations
Human XPNPEP2 / X-Pro aminopeptidase 2 Protein (His Tag) SDS-PAGE
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