WRNIP1 Polyclonal Antibody

Cat.#: 166069

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Product Information

  • Product Name
    WRNIP1 Polyclonal Antibody
  • Documents
  • Description
    Polyclonal antibody to WRNIP1
  • Tested applications
    WB
  • Species reactivity
    Human
  • Alternative names
    WRNIP1 antibody; WHIP antibody; bA420G6.2 antibody; ATPase WRNIP1 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 401-640 of human WRNIP1 (NP_569079.1).
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • Storage instructions
    Store at -20℃. Avoid freeze / thaw cycles.
  • Applications
    WB 1:1000 - 1:2000
  • Validations

    Western blot - WRNIP1 Polyclonal Antibody

    Western blot - WRNIP1 Polyclonal Antibody

    Western blot analysis of extracts of HeLa cells, using WRNIP1 antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit .Exposure time: 1s.

  • Background
    Functions as a modulator of initiation or reinitiation events during DNA polymerase delta-mediated DNA synthesis. In the presence of ATP, stimulation of DNA polymerase delta-mediated DNA synthesis is decreased. Plays also a role in the innate immune defense against viruses. Stabilizes the RIG-I/DDX58 dsRNA interaction and promotes RIG-I/DDX58 'Lys-63'-linked polyubiquitination. In turn, RIG-I/DDX58 transmits the signal through mitochondrial MAVS.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"