WRN antibody

WRN antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

WRN Rabbit Polyclonal antibody. Positive WB detected in MCF-7 cells, HEK-293 cells. Observed molecular weight by Western-blot: 162 kDa

ELISA, WB

Human; other species not tested.

DKFZp686C2056 antibody; DNA helicase antibody; RecQ like type 3 antibody; Exonuclease WRN antibody; RecQ protein like 2 antibody; RECQ3 antibody; RECQL2 antibody; RECQL3 antibody; WRN antibody

Rabbit IgG

This antibody was obtained by immunization of Peptide (Accession Number: NM_000553). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

Werner syndrome ATP dependent helicase (WRN) ,also named as RECQ3 or RecQ protein like 2, is a 1432 amino acid protein, which contains one HRDC domain, one helicase C-terminal domain, one helicase ATP-binding domain and 3’-5’ exonuclease domain. WRN localizes in the nucleoplasm and belongs to the helicase family. WRN plays a central role in the repair of methylation-induced DNA damage and has an helicase activity necessary to prevent dramatic telomere loss during DNA replication. WRN gene mutation has an association with Werner syndrome and colorectal cancer.