WDR45 Polyclonal Antibody

Cat.#: 165435

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Product Information

  • Product Name
    WDR45 Polyclonal Antibody
  • Documents
  • Description
    Polyclonal antibody to WDR45
  • Tested applications
    WB, IF
  • Species reactivity
    Human, Mouse, Rat
  • Alternative names
    WDR45 antibody; JM5 antibody; NBIA4 antibody; NBIA5 antibody; WDRX1 antibody; WIPI-4 antibody; WIPI4 antibody; WD repeat domain 45 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-360 of human WDR45 (NP_001025067.1).
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • Storage instructions
    Store at -20℃. Avoid freeze / thaw cycles.
  • Applications
    WB 1:500 - 1:2000
    IF 1:50 - 1:100
  • Validations

    Immunofluorescence - WDR45 Polyclonal Antibody

    Immunofluorescence - WDR45 Polyclonal Antibody

    Immunofluorescence analysis of A549 cells using WDR45 antibody . Blue: DAPI for nuclear staining.

  • Background
    Component of the autophagy machinery that controls the major intracellular degradation process by which cytoplasmic materials are packaged into autophagosomes and delivered to lysosomes for degradation. Activated by the STK11/AMPK signaling pathway upon starvation, WDR45 is involved in autophagosome assembly downstream of WIPI2, regulating the size of forming autophagosomes. Probably recruited to membranes through its PtdIns3P activity.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"