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Product Name
WDR4 antibody
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Description
WDR4 Rabbit Polyclonal antibody. Positive WB detected in HeLa cells, transfected cells, Transfected HEK-293 cells. Observed molecular weight by Western-blot: 30kd
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Tested applications
ELISA, WB
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
TRM82 antibody; WD repeat containing protein 4 antibody; WD repeat domain 4 antibody; WDR4 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of WDR4 recombinant protein (Accession Number: NM_001260476). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
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Validations
HeLa cells were subjected to SDS PAGE followed by western blot with Catalog No:116866(WDR4 antibody) at dilution of 1:300
Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:116866(WDR4 Antibody) at dilution of 1:1000
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Background
A group of functionally diverse regulatory proteins in eukaryotes, defined by a conserved core of 4 or more modular repeat units, is known as the WD repeat family. Proteins belonging to the WD repeat family are involved in a number of cellular processes, including cell cycle progression, apoptosis, signal transduction, and gene regulation. WD repeat-containing protein 4 (WDR4) belongs to the WD repeat family, and is required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. It acts to stablize and induce conformation change of the catalytic subunit in the complex. There exists three isoforms, while isoform1, 2 are 45kDa band, and isoform 3 is 30 kDa band.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"