VPS26B antibody

Cat.#: 116778

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Product Information

  • Product Name
    VPS26B antibody
  • Documents
  • Description
    VPS26B Rabbit Polyclonal antibody. Positive WB detected in human brain tissue. Observed molecular weight by Western-blot: 39kd
  • Tested applications
    ELISA, WB
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    Pep8b antibody; Vesicle protein sorting 26B antibody; VPS26B antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of VPS26B recombinant protein (Accession Number: NM_052875). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:500-1:5000

  • Validations

    human brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:116778(VPS26B antibody) at dilution of 1:1000

    human brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:116778(VPS26B antibody) at dilution of 1:1000

  • Background
    In mammals, there are two paralogues of yeast Vps26, VPS26A and VPS26B (PMID: 16190980). VPS26 is a component of the retromer complex composed of VPS26 (VPS26A or VPS26B), VPS29, VPS35, SNX1 and SNX2. VPS26A and VPS26B subunits define distinct retromer complexes (PMID: 21920005). The retromer complex is important in recycling transmembrane receptors from endosomes to the trans-Golgi network (TGN).
  • References
    • Gallon M, Clairfeuille T, Steinberg F. A unique PDZ domain and arrestin-like fold interaction reveals mechanistic details of endocytic recycling by SNX27-retromer. Proceedings of the National Academy of Sciences of the United States of America. 111(35):E3604-13. 2014.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"