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Product Name
VPS26A antibody
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Description
VPS26A Rabbit Polyclonal antibody. Positive IF detected in HeLa cells. Positive IHC detected in human kidney tissue, human cervical cancer tissue. Observed molecular weight by Western-blot: 38 kDa
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Tested applications
ELISA, IF, IHC
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
FLJ12930 antibody; HB58 antibody; Hbeta58 antibody; hVPS26 antibody; PEP8A antibody; Vesicle protein sorting 26A antibody; VPS26 antibody; VPS26A antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of VPS26A recombinant protein (Accession Number: NM_004896). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
IHC: 1:20-1:200
IF: 1:20-1:200
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Validations
HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:116777(VPS26A Antibody) at dilution of 1:300
Immunofluorescent analysis of HeLa cells using Catalog No:116777(VPS26A Antibody) at dilution of 1:50 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Immunohistochemistry of paraffin-embedded human kidney tissue slide using Catalog No:116777(VPS26A Antibody) at dilution of 1:200 (under 10x lens).
Immunohistochemistry of paraffin-embedded human kidney tissue slide using Catalog No:116777(VPS26A Antibody) at dilution of 1:200 (under 40x lens).
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Background
In mammals, there are two paralogues of yeast Vps26, VPS26A and VPS26B (PMID: 16190980). VPS26 is a component of the retromer complex composed of VPS26 (VPS26A or VPS26B), VPS29, VPS35, SNX1 and SNX2. VPS26A and VPS26B subunits define distinct retromer complexes (PMID: 21920005). The retromer complex is important in recycling transmembrane receptors from endosomes to the trans-Golgi network (TGN).
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