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Product Name
Mouse VDR-NR111 (His Tag) recombinant protein
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Description
Nuclear hormone receptor. Transcription factor that mediates the action of vitamin D3 by controlling the expression of hormone sensitive genes. Recruited to promoters via its interaction with BAZ1B/WSTF which mediates the interaction with acetylated histones, an essential step for VDR-promoter association. Plays a central role in calcium homeostasis.
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Protein name
Vitamin D3 receptor
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Protein short names
NR1I1; VITAMIN D3 RECEPTOR; PPP1R163; NUCLEAR RECEPTOR SUBFAMILY 1 GROUP I MEMBER 1; NR111; 25-DIHYDROXYVITAMIN D3 RECEPTOR; VITAMIN D NUCLEAR RECEPTOR VARIANT 1
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Uniprot ID
P48281
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Gene Name
Vdr; Nr1i1
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Source/Expression Host
Baculovirus-Insect Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the mouse VDR (P48281) (Met1-Ser422) was fused with a polyhistidine tag at the C-terminus.
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Protein Species
Mouse
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Molecular weight
The recombinant mouse VDR consists of 432 amino acids and has a calculated molecular mass of 49.2 kDa. The recombinant protein migrates as an approximately 55 kDa band in SDS-PAGE under reducing conditions.
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Purity
> 86 % as determined by SDS-PAGE
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Validations
Mouse VDR / NR1I1 Protein (His Tag) SDS-PAGE
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