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Product Name
Human VCL/Vinculin (His Tag) recombinant protein
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Description
Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion.
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Protein name
Vinculin
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Protein short names
RP11-178G16.3; AW545629; MVCL; 9430097D22; MV; CMH15; CMD1W; HEL114; AI462105; AA571387
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Uniprot ID
P18206
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Gene Name
VCL
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human VCL (P18206-2) (Met 1-Gln 1066) was expressed, fused with a polyhistidine tag at the C-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human VCL consists of 1077 amino acids and has a calculated molecular mass of 118 kDa. The apparent molecular mass of rhVCL is approximately 115 kDa in SDS-PAGE under reducing conditions.
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Purity
> 90 % as determined by SDS-PAGE
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Validations
Human VCL / Vinculin Protein (His Tag) SDS-PAGE
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