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Product Name
VGLL1 antibody
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Description
VGLL1 Rabbit Polyclonal antibody. Positive IHC detected in human prostate cancer tissue. Positive WB detected in Jurkat cells, human brain tissue, mouse brain tissue, mouse spleen tissue, PC-3 cells, rat brain tissue. Observed molecular weight by Western-blot: 26-29 kDa
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Tested applications
ELISA, IHC, WB
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Species reactivity
Human, Mouse, Rat; other species not tested.
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Alternative names
Protein TONDU antibody; TDU antibody; vestigial like 1 (Drosophila) antibody; Vgl 1 antibody; VGL1 antibody; VGLL1 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of VGLL1 recombinant protein (Accession Number: NM_016267). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:20-1:200
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Validations
Jurkat cells were subjected to SDS PAGE followed by western blot with Catalog No:116744(VGLL1 antibody) at dilution of 1:1000
Immunohistochemical of paraffin-embedded human prostate cancer using Catalog No:116744(VGLL1 antibody) at dilution of 1:50 (under 10x lens)
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Background
VGLL1 is a specific coactivator for the mammalian TEFs. It can bind proteins of the TEA domain family of transcription factors. Vgll1-TEFs complex upregulates the expression of IGFBP-5, a proliferation-promoting gene, and facilitates anchorage-independent cell proliferation
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References
- Castilla MÁ, López-García MÁ, Atienza MR. VGLL1 expression is associated with a triple-negative basal-like phenotype in breast cancer. Endocrine-related cancer. 21(4):587-99. 2014.
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