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Product Name
VEGFR3 antibody
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Description
VEGFR3 Rabbit Polyclonal antibody. Positive WB detected in mouse spleen tissue, HeLa cells, mouse heart tissue, PC-3 cells. Observed molecular weight by Western-blot: 125 kDa
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Tested applications
ELISA, WB
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Species reactivity
Human; other species not tested.
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Alternative names
FLT 4 antibody; FLT4 antibody; FLT41 antibody; Fms like tyrosine kinase 4 antibody; fms related tyrosine kinase 4 antibody; LMPH1A antibody; PCL antibody; VEGFR 3 antibody; VEGFR3 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Peptide (Accession Number: NM_002020). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:1000
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Validations
mouse spleen tissue were subjected to SDS PAGE followed by western blot with Catalog No:116740(FLT4 antibody) at dilution of 1:300
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Background
FLT4, also named as VEGFR-3, belongs to the protein kinase superfamily, Tyr protein kinase family and CSF-1/PDGF receptor subfamily. It is a receptor for VEGFC. FLT4 has a tyrosine-protein kinase activity. Defects in FLT4 are the cause of lymphedema hereditary type 1 (LYH1A). Defects in FLT4 are found in juvenile hemangioma. The antibody is specific to FLT4.
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References
- Zhao J, Geng YU, Hua H. Fenofibrate inhibits the expression of VEGFC and VEGFR-3 in retinal pigmental epithelial cells exposed to hypoxia. Experimental and therapeutic medicine. 10(4):1404-1412. 2015.
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