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Product Name
VDAC2 antibody
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Description
VDAC2 Rabbit Polyclonal antibody. Positive IHC detected in human prostate cancer tissue, human prostate tissue. Positive WB detected in human heart tissue, human liver tissue. Positive IP detected in mouse heart tissue. Observed molecular weight by Western-blot: 32kd
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Tested applications
ELISA, WB, IHC, IP
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
FLJ23841 antibody; hVDAC2 antibody; VDAC 2 antibody; VDAC2 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of VDAC2 recombinant protein (Accession Number: NM_001184823). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IP: 1:200-1:2000
IHC: 1:20-1:200
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Validations
human heart tissue were subjected to SDS PAGE followed by western blot with Catalog No:116730(VDAC2 antibody) at dilution of 1:500
Immunohistochemical of paraffin-embedded human prostate cancer using Catalog No:116730(VDAC2 antibody) at dilution of 1:100 (under 40x lens)
IP Result of anti-VDAC2 (IP:Catalog No:116730, 4ug; Detection:Catalog No:116730 1:500) with mouse heart tissue lysate 3200ug.
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Background
VDAC2 represents voltage-dependent anion channel 2
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References
- Petit FM, Serres C, Bourgeon F, Pineau C, Auer J. Identification of sperm head proteins involved in zona pellucida binding. Human reproduction (Oxford, England). 28(4):852-65. 2013.
- Shin DI, Oh YJ. Tumor Necrosis Factor-Associated Protein 1 (TRAP1) is Released from the Mitochondria Following 6-hydroxydopamine Treatment. Experimental neurobiology. 23(1):65-76. 2014.
- Yuan J, Zhang Y, Sheng Y, Fu X, Cheng H, Zhou R. MYBL2 guides autophagy suppressor VDAC2 in the developing ovary to inhibit autophagy through a complex of VDAC2-BECN1-BCL2L1 in mammals. Autophagy. 11(7):1081-98. 2015.
- Okazaki M, Kurabayashi K, Asanuma M, Saito Y, Dodo K, Sodeoka M. VDAC3 gating is activated by suppression of disulfide-bond formation between the N-terminal region and the bottom of the pore. Biochimica et biophysica acta. 1848(12):3188-96. 2015.
- Shiau JY, Yin SY, Chang SL. Mechanistic Study of the Phytocompound, 2- β -D-Glucopyranosyloxy-1-hydroxytrideca-5,7,9,11-tetrayne in Human T-Cell Acute Lymphocytic Leukemia Cells by Using Combined Differential Proteomics and Bioinformatics Approaches. Evidence-based complementary and alternative medicine : eCAM. 2015:475610. 2015.
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