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Product Name
Human VEGF-B (Fc Tag) recombinant protein
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Description
Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis.
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Protein name
Vascular endothelial growth factor B
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Protein short names
VEGFL; VEGF-B; VRF
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Uniprot ID
Q7LAP4
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Gene Name
VEGFB; VRF
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human VEGFB (NP_003368.1) (Pro22-Ala207) was expressed with the Fc region of human IgG1 at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human VEGFB consists 446 amino acids and predicts a molecular mass of 47.8 kDa.
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Purity
> (75.2+22) % as determined by SDS-PAGE.
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Activity
Measured by its binding ability in a functional ELISA.
Immobilized human S4-Fc3L3-VEGFB at 10 μg/ml (100 μL/well) can bind biotinylated human NRP1-Fc(Cat:500560) , The EC50 of biotinylated human NRP1-Fc(Cat:500560) is 0.03-0.07μg/mL. -
Validations
Human VEGF-B / VEGFB Protein (Fc Tag)
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