VAMP8 antibody

VAMP8 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

VAMP8 Rabbit Polyclonal antibody. Positive WB detected in HL-60 cells. Observed molecular weight by Western-blot: 15 kDa

ELISA, WB

Human,Mouse,Rat; other species not tested.

EDB antibody; Endobrevin antibody; VAMP 8 antibody; VAMP8 antibody

Rabbit IgG

This antibody was obtained by immunization of VAMP8 recombinant protein (Accession Number: NM_003761). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

VAMP8, also named as endobrevin, is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family and the SNARE (soluble NSF-attachment protein receptor) superfamily. Characterized by a common sequence called the SNARE motif, SNARE proteins are involved in membrane fusion and vesicular transport (PMID: 11252968). VAMP8 is involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane. It is required for dense-granule secretion in platelets and plays a role in regulated enzyme secretion in pancreatic acinar cells. VAMP8 is also involved in the abscission of the midbody during cell division, which leads to completely separate daughter cells.