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Product Name
USP36 antibody
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Description
USP36 Rabbit Polyclonal antibody. Positive WB detected in Jurkat cells, HeLa cells, HepG2 cells. Positive IP detected in Jurkat cells. Observed molecular weight by Western-blot: 100-123 kDa
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Tested applications
ELISA, WB, IP
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Species reactivity
Human, Mouse; other species not tested.
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Alternative names
Deubiquitinating enzyme 36 antibody; DUB1 antibody; KIAA1453 antibody; Ubiquitin thiolesterase 36 antibody; USP36 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of USP36 recombinant protein (Accession Number: BC038983). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IP: 1:200-1:1000
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Validations
Jurkat cells were subjected to SDS PAGE followed by western blot with Catalog No:116610(USP36 antibody) at dilution of 1:200
IP Result of anti-USP36 (IP:Catalog No:116610, 4ug; Detection:Catalog No:116610 1:200) with Jurkat cells lysate 1200ug.
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Background
USP36(Ubiquitin carboxyl-terminal hydrolase 36) is also named as KIAA1453, FLJ12851, DUB1 and belongs to the peptidase C19 family. It regulates the transcription and processing of rRNA by deubiquitylating various proteins involved in these processes, and the aberrant nucleolar structure in its absence is secondary to deficient ribosome biogenesis. USP36 plays a crucial role in regulating the structure and function of nucleoli.(PMID:19208757). The ubiquitin-specific protease that is required in germline, epithelial, and intestinal stem cells(PMID:19039105). It has 2 isoforms produced by alternative splicing.
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