• Human PLAUR/CD87 (His Tag) recombinant protein

Human PLAUR/CD87 (His Tag) recombinant protein

Cat.#: 501644

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Product Information

  • Product Name
    Human PLAUR/CD87 (His Tag) recombinant protein
  • Documents
  • Description
    Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form.
  • Protein name
    Urokinase plasminogen activator surface receptor
  • Protein short names
    U-PAR; UPAR; PLAUR; CD87; URKR
  • Uniprot ID
    Q03405
  • Gene Name
    PLAUR; MO3; UPAR
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human UPAR isoform 1 (Q03405-1) (Met 1-Arg 303) without the pro peptide was expressed, with a carboxy-terminal polyhistidine tag.
  • Protein Species
    Human
  • Molecular weight
    The secreted recombinant human UPAR consists of 292 amino acids with the predicted molecular mass of 32.8 kDa. As a result of glycosylation, rhUPAR migrates as an approximately 48 kDa band in SDS-PAGE under reducing conditions.
  • Purity
    > 98 % as determined by SDS-PAGE
  • Activity
    Measured by its binding ability in a functional ELISA. Immobilized human uPAR at 5 μg/ml (100 μl/well) can bind biotinylated human UPA with a linear ranger of 40-1000 ng/ml.
  • Validations

    Human uPAR / CD87 Protein (His Tag) SDS-PAGE

    Human uPAR / CD87 Protein (His Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"