• Mouse PLAUR/CD87 (His & Fc Tag) recombinant protein

Mouse PLAUR/CD87 (His & Fc Tag) recombinant protein

Cat.#: 500129

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Product Information

  • Product Name
    Mouse PLAUR/CD87 (His & Fc Tag) recombinant protein
  • Documents
  • Description
    Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA.
  • Protein name
    Urokinase plasminogen activator surface receptor
  • Protein short names
    U-PAR; UPAR; PLAUR; CD87; URKR
  • Uniprot ID
    Q545X5
  • Gene Name
    Plaur
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the extracellular domain (Met 1-Thr 297) of mouse PLAUR (NP_035243.1) precursor was fused with the C-terminal polyhistidine-tagged Fc region of human IgG1 at the C-terminus.
  • Protein Species
    Mouse
  • Molecular weight
    The recombinant mouse PLAUR/Fc is a disulfide-linked homodimer after removal of the signal peptide. The reduced monomer consists of 522 amino acids and has a predicted molecular mass of 58 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rmPLAUR/Fc monomer is approximately 80-90 kDa due to glycosylation.
  • Purity
    > 97 % as determined by SDS-PAGE
  • Activity
    Measured by its binding ability in a functional ELISA. Immobilized human uPA at 5 μg/ml (100 μl/well) can bind mouse PLAUR with a linear ranger of 1.6-40 ng/ml.
  • Validations

    Mouse PLAUR / CD87 / uPAR Protein (His & Fc Tag) SDS-PAGE

    Mouse PLAUR / CD87 / uPAR Protein (His & Fc Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"