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Product Name
Human uracil-DNA glycosylase (GST Tag) recombinant protein
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Description
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
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Protein name
Uracil-DNA glycosylase
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Protein short names
UNG15; UNG1; DGU; HIGM4; DKFZP781L1143; UDG; UNG2; URACIL-DNA GLYCOSYLASE; UNG; HIGM5
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Uniprot ID
P13051
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Gene Name
UNG; DGU; UNG1; UNG15
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human UNG isoform 1 (P13051-2) (Phe 85-Leu 304) was fused with the GST tag at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human UNG/GST chimera consists of 452 amino acids and has a predicted molecular mass of 52 kDa. It migrates as an approxiamtely 48 kDa band in SDS-PAGE under reducing conditions.
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Purity
> 90 % as determined by SDS-PAGE
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Validations
Human Uracil-DNA glycosylase / UNG Protein (GST Tag) SDS-PAGE
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