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UPK2 antibody

Cat.#: 116629

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Product Information

  • Product Name
    UPK2 antibody
  • Documents
  • Description
    UPK2 Rabbit Polyclonal antibody. Positive IHC detected in human bladder tissue. Positive WB detected in mouse testis tissue, mouse kidney tissue. Observed molecular weight by Western-blot: 28kd
  • Tested applications
    ELISA, WB, IHC
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    UP2 antibody; UPII antibody; upk 2 antibody; UPK2 antibody; uroplakin 2 antibody; Uroplakin II antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of UPK2 recombinant protein (Accession Number: NM_006760). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:2000

    IHC: 1:20-1:200

  • Validations

    mouse testis tissue were subjected to SDS PAGE followed by western blot with Catalog No:116629(UPK2 antibody) at dilution of 1:500

    mouse testis tissue were subjected to SDS PAGE followed by western blot with Catalog No:116629(UPK2 antibody) at dilution of 1:500

    Immunohistochemical of paraffin-embedded human bladder using Catalog No:116629(UPK2 antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemical of paraffin-embedded human bladder using Catalog No:116629(UPK2 antibody) at dilution of 1:50 (under 10x lens)

  • Background
    Uroplakins are a group of urothelial differentiation-related membrane proteins. They are components of the asymmetric unit membrane (AUM), which forms the apical plaques of mammalian urothelium and is believed to play a role in strengthening the urothelial apical surface thus preventing the cells from rupturing during bladder distention (PMID: 8175808). Uroplakin-2 (UPK2) is a single-pass type I membrane protein. UPK2 may play an important role in regulating the assembly of the AUM.
  • References

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"