UNC5C-Specific antibody

UNC5C-Specific antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

UNC5C-Specific Rabbit Polyclonal antibody. Positive WB detected in mouse brain tissue. Observed molecular weight by Western-blot: 50kd,103kd

ELISA, WB

human, mouse, rat; other species not tested.

UNC5C antibody; unc 5 homolog C (C. elegans) antibody; UNC5H3 antibody; Protein unc 5 homolog 3 antibody; Protein unc 5 homolog C antibody

Rabbit IgG

This antibody was obtained by immunization of Peptide (Accession Number: NM_003728). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

UNC5C, also named as UNC5H3, belongs to the unc-5 family. It is a receptor for netrin required for axon guidance. It mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also involved in corticospinal tract axon guidances independently of DCC. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. The antibody is specific to UNC5C.