-
Product Name
UMP/CMP kinase antibody
- Documents
-
Description
UMP/CMP kinase Rabbit Polyclonal antibody. Positive WB detected in human pancreas tissue, human skeletal muscle tissue. Positive IHC detected in human pancreas cancer tissue. Observed molecular weight by Western-blot: 26 kDa
-
Tested applications
ELISA, WB, IHC
-
Species reactivity
Human,Mouse,Rat; other species not tested.
-
Alternative names
CMK antibody; CMPK antibody; CMPK1 antibody; Cytidine monophosphate kinase antibody; Cytidylate kinase antibody; Deoxycytidylate kinase antibody; UCK antibody; UMK antibody; UMP CMP kinase antibody; UMP CMPK antibody; UMP/CMP kinase antibody; UMP/CMPK antibody; UMPK antibody; Uridine monophosphate kinase antibody
-
Isotype
Rabbit IgG
-
Preparation
This antibody was obtained by immunization of UMP/CMP kinase recombinant protein (Accession Number: NM_016308). Purification method: Antigen affinity purified.
-
Clonality
Polyclonal
-
Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
-
Storage instructions
Store at -20℃. DO NOT ALIQUOT
-
Applications
Recommended Dilution:
WB: 1:200-1:2000
IHC: 1:20-1:200
-
Validations
human pancreas tissue were subjected to SDS PAGE followed by western blot with Catalog No:116569(CMPK1 antibody) at dilution of 1:300
Immunohistochemical of paraffin-embedded human pancreas cancer using Catalog No:116569(CMPK1 antibody) at dilution of 1:100 (under 10x lens)
-
Background
Pyrimidine nucleoside monophosphate kinase [UMP/CMP kinase (UMP/CMPK)] (CMPK1) is also named as CMK, CMPK, UCK, UMK, UMPK and belongs to the adenylate kinase family. It plays a crucial role in the formation of UDP, CDP, and dCDP, which are required for cellular nucleic acid synthesis(PMID:11912132). CMPK1 can use a broad spectrum of phosphate donors but the best phosphate donors are ATP and dATP. The longest deduced protein contains 228 amino acids and has a calculated molecular mass of 26 kD. However, translation likely begins at the second initiation methionine, resulting in a protein of 196 amino acids(PMID:10462544). The shorter form is the endogenously translated protein(PMID:11912132).
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"