UMP/CMP kinase antibody

Cat.#: 116569

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Product Information

  • Product Name
    UMP/CMP kinase antibody
  • Documents
  • Description
    UMP/CMP kinase Rabbit Polyclonal antibody. Positive WB detected in human pancreas tissue, human skeletal muscle tissue. Positive IHC detected in human pancreas cancer tissue. Observed molecular weight by Western-blot: 26 kDa
  • Tested applications
    ELISA, WB, IHC
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    CMK antibody; CMPK antibody; CMPK1 antibody; Cytidine monophosphate kinase antibody; Cytidylate kinase antibody; Deoxycytidylate kinase antibody; UCK antibody; UMK antibody; UMP CMP kinase antibody; UMP CMPK antibody; UMP/CMP kinase antibody; UMP/CMPK antibody; UMPK antibody; Uridine monophosphate kinase antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of UMP/CMP kinase recombinant protein (Accession Number: NM_016308). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:2000

    IHC: 1:20-1:200

  • Validations

    human pancreas tissue were subjected to SDS PAGE followed by western blot with Catalog No:116569(CMPK1 antibody) at dilution of 1:300

    human pancreas tissue were subjected to SDS PAGE followed by western blot with Catalog No:116569(CMPK1 antibody) at dilution of 1:300

    Immunohistochemical of paraffin-embedded human pancreas cancer using Catalog No:116569(CMPK1 antibody) at dilution of 1:100 (under 10x lens)

    Immunohistochemical of paraffin-embedded human pancreas cancer using Catalog No:116569(CMPK1 antibody) at dilution of 1:100 (under 10x lens)

  • Background
    Pyrimidine nucleoside monophosphate kinase [UMP/CMP kinase (UMP/CMPK)] (CMPK1) is also named as CMK, CMPK, UCK, UMK, UMPK and belongs to the adenylate kinase family. It plays a crucial role in the formation of UDP, CDP, and dCDP, which are required for cellular nucleic acid synthesis(PMID:11912132). CMPK1 can use a broad spectrum of phosphate donors but the best phosphate donors are ATP and dATP. The longest deduced protein contains 228 amino acids and has a calculated molecular mass of 26 kD. However, translation likely begins at the second initiation methionine, resulting in a protein of 196 amino acids(PMID:10462544). The shorter form is the endogenously translated protein(PMID:11912132).

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"