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Product Name
UGT2B7 Polyclonal Antibody
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Description
Polyclonal antibody to UGT2B7
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Tested applications
WB, IF
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Species reactivity
Human, Mouse, Rat
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Alternative names
UGT2B7 antibody; UDPGT 2B7 antibody; UDPGT 2B9 antibody; UDPGT2B7 antibody; UDPGTH2 antibody; UDPGTh-2 antibody; UGT2B9 antibody; UDPGT2B9 antibody; UDP-glucuronosyltransferase 2B7 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 25-351 of human UGT2B7 (NP_001065.2).
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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Storage instructions
Store at -20℃. Avoid freeze / thaw cycles.
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Applications
WB 1:500 - 1:2000
IF 1:50 - 1:100 -
Validations
Western blot - UGT2B7 Polyclonal Antibody
Western blot analysis of extracts of various cell lines, using UGT2B7 antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.
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Background
UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.; Its unique specificity for 3,4-catechol estrogens and estriol suggests it may play an important role in regulating the level and activity of these potent and active estrogen metabolites. Is also active with androsterone, hyodeoxycholic acid and tetrachlorocatechol (in vitro).
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"