UGT2B15 Polyclonal Antibody
Polyclonal antibody to UGT2B15
Human, Mouse, Rat
UGT2B15 antibody; HLUG4 antibody; UDPGT 2B8 antibody; UDPGT2B15 antibody; UDPGTH3 antibody; UGT2B8 antibody; UDP-glucuronosyltransferase 2B15 antibody
Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 60-190 of human UGT2B15 (NP_001067.2).
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Store at -20℃. Avoid freeze / thaw cycles.
WB 1:500 - 1:2000
IHC 1:100 - 1:200
Western blot - UGT2B15 Polyclonal Antibody
Western blot analysis of extracts of various cell lines, using UGT2B15 antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit .Exposure time: 5s.
UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isozyme displays activity toward several classes of xenobiotic substrates, including simple phenolic compounds, 7-hydroxylated coumarins, flavonoids, anthraquinones, and certain drugs and their hydroxylated metabolites. It also catalyzes the glucuronidation of endogenous estrogens and androgens.
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