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UGP2 antibody

Cat.#: 116557

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Product Information

  • Product Name
    UGP2 antibody
  • Documents
  • Description
    UGP2 Rabbit Polyclonal antibody. Positive IHC detected in human ovary tumor tissue. Positive WB detected in HepG2 cells, HEK-293 cells, HeLa cells, mouse liver tissue. Observed molecular weight by Western-blot: 50-56kd
  • Tested applications
    ELISA, IHC, WB
  • Species reactivity
    Human, Mouse, Rat; other species not tested.
  • Alternative names
    pHC379 antibody; UDP glucose pyrophosphorylase antibody; UDPG antibody; UDPGP antibody; UDPGP2 antibody; UGP1 antibody; UGP2 antibody; UGPase antibody; UGPP2 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of UGP2 recombinant protein (Accession Number: NM_001377525). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:2000

    IHC: 1:20-1:200

  • Validations

    HepG2 cells were subjected to SDS PAGE followed by western blot with Catalog No:116557(UGP2 antibody) at dilution of 1:500

    HepG2 cells were subjected to SDS PAGE followed by western blot with Catalog No:116557(UGP2 antibody) at dilution of 1:500

    Immunohistochemical of paraffin-embedded human ovary tumor using Catalog No:116557(UGP2 antibody) at dilution of 1:100 (under 25x lens)

    Immunohistochemical of paraffin-embedded human ovary tumor using Catalog No:116557(UGP2 antibody) at dilution of 1:100 (under 25x lens)

  • Background
    UDP-glucose pyrophosphorylase 2 (UGP2, synonyms: UDPG, UGPP2, UDPGP2, Phc379)is an important intermediary in mammalian carbohydrate interconversions. It transfers a glucose moiety from glucose-1-phosphate to MgUTP and forms UDP-glucose and MgPPi. In liver and muscle tissue, UDP-glucose is a direct precursor of glycogen; in lactating mammary gland it is converted to UDP-galactose which is then converted to lactose. So far two isoforms are encoded by two transcript variants have been found.
  • References
    • Kakehashi A, Ishii N, Shibata T. Mitochondrial prohibitins and septin 9 are implicated in the onset of rat hepatocarcinogenesis. Toxicological sciences : an official journal of the Society of Toxicology. 119(1):61-72. 2011.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"