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Product Name
UCK2 antibody
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Description
UCK2 Rabbit Polyclonal antibody. Positive IP detected in Jurkat cells. Positive WB detected in Jurkat cells. Observed molecular weight by Western-blot: 33-35 kDa
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Tested applications
ELISA, WB, IP
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
Cytidine monophosphokinase 2 antibody; Testis specific protein TSA903 antibody; TSA903 antibody; UCK 2 antibody; UCK2 antibody; UMPK antibody; uridine cytidine kinase 2 antibody; Uridine monophosphokinase 2 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of UCK2 recombinant protein (Accession Number: NM_012474). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IP: 1:200-1:2000
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Validations
Jurkat cells were subjected to SDS PAGE followed by western blot with Catalog No:116676(UCK2 antibody) at dilution of 1:500
IP Result of anti-UCK2 (IP:Catalog No:116676, 4ug; Detection:Catalog No:116676 1:500) with Jurkat cells lysate 4000ug.
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Background
Uridine-cytidine kinase 2 catalyzes the phosphorylation of uridine and cytidine to uridine monophosphate (UMP) and cytidine monophosphate (CMP), respectively. This is the first step in the production of the pyrimidine nucleoside triphosphates required for RNA and DNA synthesis. UCK2 belongs to the uridine kinase family and UCK have important roles for the phosphorylation of nucleoside analogs that may be important in chemotherapy of cancer.
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References
- Sripayap P, Nagai T, Uesawa M. Mechanisms of resistance to azacitidine in human leukemia cell lines. Experimental hematology. 42(4):294-306.e2. 2014.
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