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Product Name
UBE2D3 antibody
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Description
UBE2D3 Rabbit Polyclonal antibody. Positive IHC detected in human prostate cancer tissue. Positive WB detected in human brain tissue, HEK-293 cells, HeLa cells, human heart tissue, Jurkat cells. Observed molecular weight by Western-blot: 17 kDa
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
E2(17)KB3 antibody; UBC4/5 antibody; UBC5C antibody; UBCH5C antibody; UBE2D3 antibody; Ubiquitin carrier protein D3 antibody; Ubiquitin protein ligase D3 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of UBE2D3 recombinant protein (Accession Number: NM_181889). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:1000-1:10000
IHC: 1:20-1:200
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Validations
human brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:116519(UBE2D3 antibody) at dilution of 1:500
Immunohistochemical of paraffin-embedded human prostate cancer using Catalog No:116519(UBE2D3 antibody) at dilution of 1:100 (under 10x lens)
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Background
UBE2D3(Ubiquitin-conjugating enzyme E2 D3) is also named as UBC5C, UBCH5C and belongs to the ubiquitin-conjugating enzyme family.It accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins.It has 3 isoforms produced by alternative splicing.
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References
- Weinert BT, Wagner SA, Horn H. Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation. Science signaling. 4(183):ra48. 2011.
- Guan GG, Wang WB, Lei BX. UBE2D3 is a positive prognostic factor and is negatively correlated with hTERT expression in esophageal cancer. Oncology letters. 9(4):1567-1574. 2015.
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