U2AF1L4 Polyclonal Antibody

U2AF1L4 Polyclonal Antibody

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• Material Safety Data Sheets (MSDS)

Polyclonal antibody to U2AF1L4

WB, IF

Human

U2AF1L4 antibody; U2AF1-RS3 antibody; U2AF1L3 antibody; U2AF1L3V1 antibody; U2AF1RS3 antibody; U2af26 antibody; splicing factor U2AF 26 kDa subunit antibody

Rabbit IgG

Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-202 of human U2AF1L4 (NP_659424.2).

Polyclonal

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Store at -20℃. Avoid freeze / thaw cycles.

WB 1:500 - 1:2000
IF 1:50 - 1:100

RNA-binding protein that function as a pre-mRNA splicing factor. Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. Acts by enhancing the binding of U2AF2 to weak pyrimidine tracts. Also participates in the regulation of alternative pre-mRNA splicing. Activates exon 5 skipping of PTPRC during T-cell activation; an event reversed by GFI1. Binds to RNA at the AG dinucleotide at the 3'-splice site (By similarity). Shows a preference for AGC or AGA (By similarity).