Cart 2
  • Human CD137 / 4-1BB (His & Fc Tag) recombinant protein

Human CD137 / 4-1BB (His & Fc Tag) recombinant protein

Cat.#: 501699

Special Price 307.5 USD

Availability: In Stock
- +

Add to cart to get an online quotation

Product Information

  • Product Name
    Human CD137 / 4-1BB (His & Fc Tag) recombinant protein
  • Documents
  • Description
    Receptor for TNFSF9/4-1BBL. Possibly active during T cell activation.
  • Protein name
    Tumor necrosis factor receptor superfamily member 9
  • Protein short names
    LY63; ILA; TNFRSF9; RP23-272N19.6; A930040I11RIK; MGC2172; AI325004; CDW137; CD137; 4-1BB; AA408498
  • Uniprot ID
    Q07011
  • Gene Name
    TNFRSF9; CD137; ILA
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the N-terminal fragment (Met 1-Gln 186) of the extracellular domain of human 4-1BB (NP_001552.2) was fused with the C-terminal polyhistidine-tagged Fc region of human IgG1 at the C-terminus.
  • Protein Species
    Human
  • Molecular weight
    The recombinant human 4-1BB/Fc chimera is a disulfide-linked homodimeric protein. The reduced monomer consists of 409 amino acids and has a calculated molecular mass of 45.2 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh4-1BB/Fc monomer is approximately 60-65 kDa due to glycosylation.
  • Purity
    > 95 % as determined by SDS-PAGE
  • Activity
    Measured by its binding ability in a functional ELISA. Immobilized recombinant mouse 4-1BB Ligand at 20 μg/ml (100 μl/well) can bind human 4-1BB with a linear range of 15.6-500 ng/ml.
  • Validations

    Human CD137 / 4-1BB / TNFRSF9 Protein (His & Fc Tag) SDS-PAGE

    Human CD137 / 4-1BB / TNFRSF9 Protein (His & Fc Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"