-
Product Name
Mouse 4-1BBL / CD137L (His Tag) recombinant protein
- Documents
-
Description
Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages.
-
Protein name
Tumor necrosis factor ligand superfamily member 9
-
Protein short names
CD137L; 4-1BBL; 4-1BB-L; AI848817; LY63L; TNFSF9
-
Uniprot ID
Q3U1Z9
-
Gene Name
Tnfsf9; Cd137l; Cd157l; Ly63l
-
Source/Expression Host
Human Cells
-
Expression Plasmid/cDNA
A DNA sequence encoding the extracellular domain (Arg 104-Glu 309) of mouse TNFSF9 (NP_033430.1) precursor was expressed with a N-terminal polyhistidine tag.
-
Protein Species
Mouse
-
Molecular weight
The secreted recombinant mouse TNFSF9 consists of 222 amino acids and has a calculated molecular mass of 25 kDa. As a result of glycosylation, the recombinant protein migrates as an approximately 40-45 kDa protein in SDS-PAGE under reducing conditions.
-
Purity
> 97 % as determined by SDS-PAGE
-
Activity
Measured by its binding ability in a functional ELISA. Immobilized recombinant mouse 4-1BB Ligand at 20 μg/ml (100ul/well) can bind human 4-1BB with a linear range of 15.6-500 ng/ml.
-
Validations
Mouse 4-1BBL / CD137L / TNFSF9 Protein (His Tag) SDS-PAGE
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"