Rat TNF-alpha/TNFA recombinant protein

Cat.#: 500921

Size:

Special Price 189.8 USD

Availability: In Stock
- +

Add to cart to get an online quotation

Product Information

  • Product Name
    Rat TNF-alpha/TNFA recombinant protein
  • Documents
  • Description
    Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation.
  • Protein name
    Tumor necrosis factor
  • Protein short names
    DADB-70P7.1; TNF; TNFSF1A; DIF; MGC151434; TNFSF2; TNFA; TNF-A; TNF-ALPHA; TNFALPHA
  • Uniprot ID
    P16599
  • Gene Name
    Tnf; Tnfa; Tnfsf2
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the mature form of rat TNF? (P16599) (Leu 80-Leu 235) was expressed and purified, with an initial Met at the N-terminus.
  • Protein Species
    Rat
  • Molecular weight
    The recombinant rat TNF? consisting of 157 amino acids and has a calculated molecular mass of 17.4 kDa. It migrates as an approximately 15 kDa band in SDS-PAGE under reducing conditions.
  • Purity
    > 93 % as determined by SDS-PAGE
  • Activity
    Measured in a cytotoxicity assay using L929 mouse fibrosarcoma cells in the presence of the metabolic inhibitor actinomycin D.
    The ED50 for this effect is typically 0.01-0.02 ng/mL.
  • Validations

    Rat TNF-alpha / TNFA Protein SDS-PAGE

    Rat TNF-alpha / TNFA Protein SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"